Tag: mots-c

MOTS-c activates AMPK and drives mitochondrial biogenesis. SS-31 protects cardiolipin in the inner mitochondrial membrane and restores electron transport efficiency in aged mitochondria. One makes more mitochondria; the other fixes the ones you have.

MOTS-c is encoded in the mitochondrial genome — not the nuclear genome — making it one of the most unusual peptides in biology. It declines with age, correlates with longevity markers in human populations, and mimics exercise at the molecular level.