Repair & Recovery
TB-500
Thymosin Beta-4 Fragment (Ac-LKKTETQ)
Evidence tier: Animal studies. Parent compound (Thymosin Beta-4) reached Phase II human trials.
| Molecular weight | 2107.4 Da |
| Molecular formula | C38H68N10O14 |
| CAS number | 885340-08-9 |
| Half-life | Unknown |
| Administration | subcutaneous, intramuscular |
| Research dose | 2–2.5 mg twice weekly (loading phase 4–6 weeks); 2 mg weekly (maintenance) |
Amino Acid Sequence
Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln
Primary Mechanism
G-actin sequestration, cell migration, MMP-2 upregulation, anti-inflammatory via NF-κB
Studied For
tendon repairmuscle repairwound healingcardiac repairneuroprotection
Reconstitution
Reconstitute with bacteriostatic water. For a 5 mg vial add 2 mL BW for a 2,500 µg/mL solution.
Storage
Lyophilised: store at -20°C. Reconstituted: refrigerate at 2–8°C, use within 30 days. Avoid freeze-thaw cycles.
Notes
TB-500 is a synthetic fragment of the full Thymosin Beta-4 protein. Human trial data exists for Tβ4 (corneal healing, cardiac), not directly for the fragment.
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These products are sold for research purposes only and are not intended for human consumption.