← Peptide Index
GH Secretagogue

Ipamorelin

Ipamorelin (Aib-His-D-2-Nal-D-Phe-Lys-NH2)

Evidence tier: Human clinical data. Studied for GH deficiency and post-operative ileus.
Molecular weight711.85 Da
Molecular formulaC38H49N9O5
CAS number170851-70-4
Half-life~2 hours
Administrationsubcutaneous
Research dose100–300 µg per dose, typically once daily pre-sleep

Amino Acid Sequence

Aib-His-D-2-Nal-D-Phe-Lys-NH2

Primary Mechanism

Ghrelin receptor (GHS-R1a) agonism — selective GH secretagogue with minimal cortisol or prolactin effect

Studied For

growth hormone secretionbody compositionsleep qualityrecoverybone density

Reconstitution

Reconstitute with bacteriostatic water. For a 5 mg vial add 2.5 mL BW for a 2,000 µg/mL solution.

Storage

Lyophilised: store at -20°C. Reconstituted: refrigerate at 2–8°C, use within 30 days.

Notes

Considered more selective than earlier GH secretagogues — does not significantly raise cortisol or prolactin. Typically stacked with CJC-1295 (no-DAC) for a synergistic GH pulse.

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