Longevity

GHK-Cu

Glycyl-L-histidyl-L-lysine Copper Complex

Evidence tier: Strong in vitro and animal data. Some human data for topical wound healing and skin applications.

Molecular weight	340.38 Da
Molecular formula	C14H24CuN6O4
CAS number	89030-95-5
Half-life	Unknown
Administration	subcutaneous, topical
Research dose	Systemic: 1–2 mg several times per week. Topical: concentrations of 0.1–1% in carrier.

Amino Acid Sequence

Gly-His-Lys

Primary Mechanism

Copper-dependent activation of 30+ genes involved in tissue repair, DNA repair, anti-inflammatory signalling, tumour suppression pathways

Studied For

wound healingskin repairanti-ageingDNA damage repairanti-inflammatoryhair growth

Reconstitution

Reconstitute with sterile or bacteriostatic water. Typically used at lower concentrations than repair peptides.

Storage

Lyophilised: store at -20°C. Reconstituted: refrigerate, use within 2 weeks. Light-sensitive — store in dark.

Notes

Endogenous peptide — plasma levels decline ~1000-fold between ages 20 and 60. Activates TGF-β, VEGF, and numerous antioxidant genes. Loren Pickart research group is primary source.

This page contains affiliate links. If you purchase through these links, I may earn a commission at no extra cost to you.

These products are sold for research purposes only and are not intended for human consumption.