Cognitive
Dihexa
N-hexanoic-Tyr-Ile-(6) aminohexanoic amide
Evidence tier: Animal studies only (primarily Alzheimer's models). No human data.
| Molecular weight | 540.72 Da |
| Molecular formula | C29H48N4O5 |
| CAS number | 1191576-03-0 |
| Half-life | Unknown; reported to be long-acting |
| Administration | oral, transdermal |
| Research dose | Extremely low doses used in animal studies (mg/kg). Human researcher doses are highly speculative. |
Amino Acid Sequence
Hexanoyl-Tyr-Ile-Ahx-NH2
Primary Mechanism
HGF/c-Met potentiation, BDNF mimetic effect, synaptogenesis promotion
Studied For
cognitive enhancementAlzheimer's disease (animal)synaptogenesisneurodegeneration
Reconstitution
Lipophilic — dissolves in DMSO, ethanol, or oil-based carriers. Not water-soluble.
Storage
Store at -20°C. Stable for 24+ months lyophilised. Protect from light.
Notes
Developed at Washington State University. Reported to be ~7 orders of magnitude more potent than BDNF at promoting synaptogenesis in vitro. Very limited safety data. Approach with significant caution.
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