GH Secretagogue

CJC-1295

CJC-1295 (Modified GRF 1-29)

Evidence tier: Human clinical trials exist. Phase II data for GHRH analog activity.
Molecular weight3647.3 Da
Molecular formulaC165H269N47O46
CAS number863288-34-0
Half-life~6–8 days (DAC form); ~30 minutes (no-DAC / Mod-GRF 1-29)
Administrationsubcutaneous
Research dose1–2 mg per week (DAC form). Often paired with Ipamorelin.

Amino Acid Sequence

Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2 (DAC form)

Primary Mechanism

GHRH receptor agonism — stimulates pituitary GH release

Studied For

growth hormone secretionbody compositionsleep qualityrecovery

Reconstitution

Reconstitute with bacteriostatic water. For a 2 mg vial add 1 mL BW for a 2,000 µg/mL solution.

Storage

Lyophilised: store at -20°C. Reconstituted: refrigerate at 2–8°C, use within 30 days.

Notes

DAC (Drug Affinity Complex) version has extended half-life via albumin binding. No-DAC version (Mod-GRF 1-29) has short half-life and is typically dosed pre-sleep. Commonly stacked with Ipamorelin for synergistic GH pulse.

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